| The association of macro- and microstructure of the corpus callosum and language lateralisation [An article from: Brain and Language] |  | Authors: R. Westerhausen, F. Kreuder, S.D. Santos Sequeira
Publisher: Elsevier
Category: Book
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Format: HTML
Media: Digital
Pages: 10
Publication Date: April 1, 2006
Availability: Available for download now
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Product Description
This digital document is a journal article from Brain and Language, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.
Description:
The present study aimed to examine how differences in functional lateralisation of language are related to interindividual variations in interhemispheric connectivity. Utilising an fMRI silent word-generation paradigm, 89 left- and right-handed subjects were subdivided into four lateralisation subgroups. Applying morphological and diffusion-tensor MRI, midsagittal cross-sectional area as well as quantitative measures of molecular diffusion (anisotropy, mean diffusion) of the corpus callosum were determined to assess interhemispheric connectivity. Statistical analyses revealed group differences in molecular diffusion but not in callosal size, which may be interpreted to reflect a stronger and/or faster interhemispheric connection in strongly left-lateralised subjects as compared to moderately left-lateralised, bilateral, or moderately right-lateralised subjects.
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